Article · 1994
“Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis”
Publication
- Title
- “Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis”
- Author
- Allen Steere (Columbia College, Class of 1965)
- Form
- Article
- First published
- 1994
- Publisher
- New England Journal of Medicine 330:229–34
- Note
- established PCR as diagnostic gold standard
Complete works of Allen Steere (127)
- 1975 Handwashing Practices for the Prevention of Nosocomial Infections · Annals of Internal Medicine
- 1977 Erythema Chronicum Migrans and Lyme Arthritis: Cryoimmunoglobulins and Clinical Activity of Skin and Joints · Science
- 1977 Erythema chronicum migrans and Lyme arthritis: the enlarging clinical spectrum · Annals of Internal Medicine
- 1977 Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities · Arthritis & Rheumatism
- 1977 “An Epidemic of Oligoarticular Arthritis in Children and Adults in Three Connecticut Communities” · Original case-cluster paper describing what became known as Lyme arthritis
- 1978 Erythema Chronicum Migrans and Lyme Arthritis: Epidemiologic Evidence for a Tick Vector1 · American Journal of Epidemiology
- 1978 Lyme Arthritis: A New Clinical Entity · Hospital Practice
- 1978 “Lyme arthritis: epidemiologic evidence for a tick vector” · American Journal of Epidemiology 108:312–21
- 1979 Acute monocytic arthritis · Arthritis & Rheumatism
- 1979 Cases of Lyme Disease in the United States: Locations Correlated with Distribution of Ixodes dammini · Annals of Internal Medicine
- 1979 Immune Complexes and the Evolution of Lyme Arthritis · New England Journal of Medicine
- 1979 Invasive Aspergillosis in Acute Leukemia: Correlation with Nose Cultures and Antibiotic Use · Annals of Internal Medicine
- 1979 “Neurologic abnormalities of Lyme disease” · Medicine (Baltimore) 58:281–94
- 1980 Antibiotic therapy in Lyme disease · Annals of Internal Medicine
- 1980 “Lyme carditis: cardiac abnormalities of Lyme disease” · Annals of Internal Medicine 93:8–16
- 1983 Neurologic Abnormalities of Lyme Disease: Successful Treatment with High-Dose Intravenous Penicillin · Annals of Internal Medicine
- 1983 Symmetric polyarthritis associated with heterophile‐negative infectious mononucleosis · Arthritis & Rheumatism
- 1983 The early clinical manifestations of Lyme disease · Annals of Internal Medicine
- 1983 The spirochetal etiology of Lyme disease · New England Journal of Medicine
- 1983 “Treatment of the early manifestations of Lyme disease” · Annals of Internal Medicine 99:22–6
- 1985 Arthritis caused by Borrelia burgdorferi in dogs · Journal of the American Veterinary Medical Association
- 1985 Diagnosing early lyme disease · The American Journal of Medicine
- 1985 Successful parenteral penicillin therapy of established Lyme arthritis · New England Journal of Medicine
- 1985 The triad of neurologic manifestations of Lyme disease · Neurology
- 1986 The spectrum of organ and systems pathology in human lyme disease · Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology
- 1986 Ultrastructural differences among spirochetes isolated from patients with Lyme disease and related disorders, and from Ixodes ricinus · Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology
- 1987 CNS manifestations of third stage lyme disease · Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology
- 1987 The Clinical Evolution of Lyme Arthritis · Annals of Internal Medicine
- 1987 “Ceftriaxone as effective therapy in refractory Lyme disease” · Journal of Infectious Diseases 155:1322–5
- 1988 Clinical Pathologic Correlations of Lyme Disease by Stage · Annals of the New York Academy of Sciences
- 1988 Lyme Myositis: Muscle Invasion by Borrelia burgdorferi · Annals of Internal Medicine
- 1988 Pathogenesis of Lyme Arthritis Implications for Rheumatic Diseasea · Annals of the New York Academy of Sciences
- 1988 Serodiagnosis of Early Lyme Disease: Analysis of IgM and IgG Antibody Responses by Using an Antibody-Capture Enzyme Immunoassay · The Journal of Infectious Diseases
- 1988 Spirochetal antigens and lymphoid cell surface markers in lyme synovitis · Arthritis & Rheumatism
- 1988 “Seronegative Lyme disease: dissociation of specific T- and B-lymphocyte responses to Borrelia burgdorferi” · New England Journal of Medicine 319:1441–6
- 1989 Lyme Disease · New England Journal of Medicine
- 1990 Association of Chronic Lyme Arthritis with HLA-DR4 and HLA-DR2 Alleles · New England Journal of Medicine
- 1990 Chronic Neurologic Manifestations of Lyme Disease · New England Journal of Medicine
- 1991 Neutrophil chemotactic factors in synovial fluids of patients with lyme disease · Arthritis & Rheumatism
- 1991 Spirochetes in atrophic skin lesions accompanied by minimal host response in a child with Lyme disease · Journal of the American Academy of Dermatology
- 1991 T cell responses to polypeptide fractions of Borrelia burgdorferi in patients with lyme arthritis · Arthritis & Rheumatism
- 1991 The Long-Term Course of Lyme Arthritis in Children · New England Journal of Medicine
- 1991 The T-Cell Proliferative Assay in the Diagnosis of Lyme Disease · Annals of Internal Medicine
- 1992 Clinical and electrophysiologic findings in chronic neuropathy of Lyme disease · Neurology
- 1992 Lyme Disease Associated with Fibromyalgia · Annals of Internal Medicine
- 1992 “Comparison of cefuroxime axetil and doxycycline in the treatment of early Lyme disease” · Annals of Internal Medicine 117:273–80
- 1993 Current Understanding of Lyme Disease · Hospital Practice
- 1993 Effectiveness of early lyme disease treatment · The American Journal of Medicine
- 1993 The Overdiagnosis of Lyme Disease · JAMA: The Journal of the American Medical Association
- 1993 The Overdiagnosis of Lyme Disease-Reply · JAMA: The Journal of the American Medical Association
- 1993 Western Blotting in the Serodiagnosis of Lyme Disease · Journal of Infectious Diseases
- 1994 Lyme disease: a growing threat to urban populations. · Proceedings of the National Academy of Sciences
- 1994 Pathogenesis, Diagnosis and Treatment of Lyme Arthritis · Lyme Borreliosis
- 1994 Treatment of Lyme arthritis · Arthritis & Rheumatism
- 1994 “Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis” · New England Journal of Medicine 330:229–34 this record
- 1995 Musculoskeletal manifestations of Lyme disease · The American Journal of Medicine
- 1996 Treatment of Chronic Lyme Disease · Science
- 1997 Diagnosis and Treatment of Lyme Arthritis · Medical Clinics of North America
- 1997 “Specific issues in the design and implementation of an efficacy trial for a Lyme disease vaccine” · Clinical Infectious Diseases 25 Suppl 1:S66–70
- 1998 7 Lyme disease · Biomedical Research Reports
- 1998 Guidelines for the Clinical Diagnosis of Lyme Disease · Annals of Internal Medicine
- 1998 Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis · Science
- 1998 Neurocognitive abnormalities in children after classic manifestations of Lyme disease · The Pediatric Infectious Disease Journal
- 1998 T Helper 1 Response Is Dominant and Localized to the Synovial Fluid in Patients with Lyme Arthritis · The Journal of Immunology
- 1998 Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant · New England Journal of Medicine
- 1998 “Lack of cardiac manifestations among patients with previously treated Lyme disease” · Annals of Internal Medicine 128:346–53
- 1999 Cross-Reactivity of Borrelia burgdorferi and Myelin Basic Protein-Specific T Cells Is Not Observed in Borrelial Encephalomyelitis · Cellular Immunology
- 1999 Successful Treatment of Lyme Encephalopathy with Intravenous Ceftriaxone · The Journal of Infectious Diseases
- 2001 Autoimmune Mechanisms in Antibiotic Treatment-Resistant Lyme Arthritis · Journal of Autoimmunity
- 2001 Expression of Adhesion Molecules in Synovia of Patients with Treatment-Resistant Lyme Arthritis · Infection and Immunity
- 2001 Optic Neuropathy in Children With Lyme Disease · Pediatrics
- 2001 Recognition of Multiple Antibody Epitopes throughout Borrelia burgdorferi p66, a Candidate Adhesin, in Patients with Early or Late Manifestations of Lyme Disease · Infection and Immunity
- 2002 A 58-Year-Old Man With a Diagnosis of Chronic Lyme Disease · JAMA
- 2002 Cerebellar ataxia as the presenting manifestation of lyme disease · The Pediatric Infectious Disease Journal
- 2002 Microbiologically Confirmed Early Lyme Disease · Annals of Internal Medicine
- 2003 Asymptomatic Infection with Borrelia burgdorferi · Clinical Infectious Diseases
- 2003 Duration of Antibiotic Therapy for Lyme Disease · Annals of Internal Medicine
- 2003 Persistence of the Antibody Response to the VlsE Sixth Invariant Region (IR6) Peptide ofBorrelia burgdorferiafter Successful Antibiotic Treatment of Lyme Disease · The Journal of Infectious Diseases
- 2003 The Presenting Manifestations of Lyme Disease and the Outcomes of Treatment · New England Journal of Medicine
- 2003 The reply: · The American Journal of Medicine
- 2004 Elucidation of Lyme arthritis · Nature Reviews Immunology
- 2004 Infection and Autoimmunity in Patients with Antibiotic Treatment-Resistant Lyme Arthritis · Infection and Autoimmunity
- 2004 Molecular characterization of the OspA161–175 T cell epitope associated with treatment-resistant Lyme arthritis: differences among the three pathogenic species of Borrelia burgdorferi sensu lato · Journal of Autoimmunity
- 2004 The emergence of Lyme disease · Journal of Clinical Investigation
- 2004 The VlsE (IR6) Peptide ELISA in the Serodiagnosis of Lyme Facial Paralysis · Otology & Neurotology
- 2005 In Situ Diversification of the Antibody Repertoire in Chronic Lyme Arthritis Synovium · The Journal of Immunology
- 2005 “Diagnosis of Lyme borreliosis” · Clinical Infectious Diseases 41:1089–134
- 2006 Lyme borreliosis in 2005, 30 years after initial observations in Lyme Connecticut · Wiener klinische Wochenschrift
- 2006 Therapy for Lyme arthritis: Strategies for the treatment of antibiotic‐refractory arthritis · Arthritis & Rheumatism
- 2006 “Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide” · Journal of Experimental Medicine 203:961–71
- 2006 “The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: IDSA clinical practice guidelines” · Clinical Infectious Diseases 43:1089–134
- 2007 High levels of inflammatory chemokines and cytokines in joint fluid and synovial tissue throughout the course of antibiotic‐refractory lyme arthritis · Arthritis & Rheumatism
- 2007 “A critical appraisal of ‘chronic Lyme disease’” · New England Journal of Medicine 357:1422–30
- 2007 “Human homologues of a Borrelia T cell epitope associated with antibiotic-refractory Lyme arthritis” · Molecular Immunology 45:180–9
- 2008 Lyme disease vaccines · Vaccines
- 2008 Prospective Study of Serologic Tests for Lyme Disease · Clinical Infectious Diseases
- 2008 Reply to letter by Volkman commenting on the possible onset of seronegative disease in Lyme arthritis · Arthritis & Rheumatism
- 2008 Reply to Stricker and Johnson · Clinical Infectious Diseases
- 2009 S.71. HLA-DRB1-Presented Peptides in Inflamed Synovium from Patients with Rheumatoid Arthritis or Antibiotic-Refractory Lyme Arthritis · Clinical Immunology
- 2010 Borrelia burgdorferi (Lyme Disease, Lyme Borreliosis) · Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
- 2011 Relationship between Immunity to Borrelia burgdorferi Outer-surface Protein A (OspA) and Lyme Arthritis · Clinical Infectious Diseases
- 2011 “A case revealing the natural history of untreated Lyme disease” · Nature Reviews Rheumatology 7:110–2
- 2012 Association of a Toll‐like receptor 1 polymorphism with heightened Th1 inflammatory responses and antibiotic‐refractory Lyme arthritis · Arthritis & Rheumatism
- 2012 Reinfection versus Relapse in Lyme Disease · New England Journal of Medicine
- 2012 SP0177 Lyme disease – old and new insights · Annals of the Rheumatic Diseases
- 2013 Dysregulation of CD4+CD25 high T Cells in the Synovial Fluid of Patients With Antibiotic‐Refractory Lyme Arthritis · Arthritis & Rheumatism
- 2013 Natural killer cells and natural killer T cells in Lyme arthritis · Arthritis Research & Therapy
- 2013 “Endothelial cell growth factor as a driving autoantigen in Lyme arthritis” · Journal of Experimental Medicine 210:2183–98
- 2014 Lyme Borreliosis · Tick-Borne Diseases of Humans
- 2015 Infection and Autoimmunity in Antibiotic-Refractory Lyme Arthritis · Infection and Autoimmunity
- 2015 Lyme Disease (Lyme Borreliosis) Due to Borrelia burgdorferi · Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
- 2016 “Autoimmune mechanisms in antibiotic refractory Lyme arthritis” · Journal of Autoimmunity 65:1–10
- 2016 “Matrix metalloproteinase 10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis” · Journal of Autoimmunity 69:24–37
- 2017 miR-155 and let-7a potentiate auto-inflammatory and tumor-like proliferative dysregulation in post-infectious Lyme arthritis synovial tissue · The Journal of Immunology
- 2017 Reply to Naktin · Clinical Infectious Diseases
- 2019 “Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis” · PNAS 116:13498–507
- 2020 Posttreatment Lyme disease syndromes: distinct pathogenesis caused by maladaptive host responses · Journal of Clinical Investigation
- 2020 “IDSA / AAN / ACR 2020 guidelines for the prevention, diagnosis, and treatment of Lyme disease” · Clinical Infectious Diseases 72:e1–e48
- 2020 “Lyme disease (Lyme borreliosis) due to Borrelia burgdorferi” (chapter) · in Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 9th ed., Elsevier
- 2021 Laboratory Diagnosis of Lyme Borreliosis · Clinical Microbiology Reviews
- 2022 Lyme Arthritis · Infectious Disease Clinics of North America
- 2022 Management of Pediatric Lyme Disease: Updates From 2020 Lyme Guidelines · Pediatrics
- 2023 Heightened Proinflammatory Glycosylation of Borrelia burgdorferi IgG Antibodies in Synovial Fluid in Patients With Antibiotic‐Refractory Lyme Arthritis · Arthritis & Rheumatology
- 2023 Lyme · A Clinician's Pearls & Myths in Rheumatology
- 2023 “Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis” · Journal of Clinical Investigation 133:e161170
- 2024 Lyme Arthritis: A 50-Year Journey · The Journal of Infectious Diseases
- 2024 Wider recognition and greater understanding of postinfectious, antibiotic-refractory Lyme arthritis · Journal of Clinical Investigation
Cite this record
Steere, Allen. “Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis”. New England Journal of Medicine 330:229–34, 1994.
Foundation record: https://philolexianfoundation.org/members/steere-allen-cc-1965/detection-of-borrelia-burgdorferi-dna-by-polymerase-chain-reaction-in-synovial-f-1994.html